Bladder, ureter & renal pelvis
General
Staging-ureter carcinoma
Last author update: 27 January 2023
Last staff update: 27 January 2023
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Ureter carcinoma AJCC staging
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Cite this page: Zynger D. Staging-ureter carcinoma. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/bladderstagingureters.html. Accessed June 7th, 2023.
Definition / general
- All carcinomas of the ureter are covered by this staging system
Essential features
- AJCC 7th edition staging was sunset on December 31, 2017; as of January 1, 2018, use of the 8th edition is mandatory
ICD coding
- ICD-10: C66.9 - malignant neoplasm of unspecified ureter
Primary tumor (pT)
- pTX: cannot be assessed
- pT0: no evidence of primary tumor
- pTa: noninvasive papillary carcinoma
- pTis: carcinoma in situ
- pT1: invades lamina propria
- pT2: invades muscularis propria
- pT3: invades periureteric fat
- pT4: invades adjacent organs or perinephric fat
Regional lymph nodes (pN)
- pNX: cannot be assessed
- pN0: no regional lymph node metastasis
- pN1: 1 lymph node with tumor deposit ≤ 2 cm
- pN2: 1 lymph node with tumor deposit > 2 cm or metastases in multiple nodes
Notes:
- Regional lymph nodes include hilar, periureteral, paracaval, iliac (common, internal / hypogastric, external), pelvic
Prefixes
- y: preoperative radiotherapy or chemotherapy
- r: recurrent tumor stage
AJCC prognostic stage groups
| Stage group 0a: | | Ta | | N0 | | M0
|
| Stage group 0is: | | Tis | | N0 | | M0
|
| Stage group I: | | T1 | | N0 | | M0
|
| Stage group II: | | T2 | | N0 | | M0
|
| Stage group III: | | T3 | | N0 | | M0
|
| Stage group IV: | | T4 | | NX - 2 | | M0 - 1
|
| | TX - 4 | | N1 - 2 | | M0 - 1
|
| | TX - 4 | | NX - 2 | | M1
|
Registry data collection variables
- Extranodal extension
- Size of largest tumor deposit within a lymph node
- Total number of lymph nodes
- Presence of carcinoma in situ
- Presence of noninvasive papillary carcinoma
- Lymphovascular invasion
- Urothelial carcinoma grade (high / low)
- Squamous cell / adenocarcinoma grade (1 - 3)
- Intratubular renal in situ spread
Histologic grade (G)
- Urothelial carcinoma
- LG: low grade
- HG: high grade
- Squamous cell / adenocarcinoma
- GX: cannot be assessed
- G1: well differentiated
- G2: moderately differentiated
- G3: poorly differentiated
Histopathologic type
- Noninvasive urothelial carcinoma
- Low grade papillary urothelial carcinoma
- High grade papillary urothelial carcinoma
- Urothelial carcinoma in situ
- Invasive urothelial carcinoma
- Conventional urothelial carcinoma
- Urothelial carcinoma variants
- Squamous cell carcinoma
- Adenocarcinoma
- Small cell carcinoma
Board review style question #1
A urothelial carcinoma of the ureter at the deepest point of invasion involves the muscularis propria. Which is the correct pT category?
- pT1
- pT2
- pT3
- pT4
Board review style answer #1
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