Bone & joints

Osteomyelitis

Tuberculous osteomyelitis



Last author update: 1 August 2013
Last staff update: 28 January 2022

Copyright: 2003-2023, PathologyOutlines.com, Inc.

PubMed Search: Tuberculous osteomyelitis[title]

Dariusz Borys, M.D.
Page views in 2022: 4,666
Page views in 2023 to date: 304
Cite this page: Borys D. Tuberculous osteomyelitis. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/boneTBosteo.html. Accessed January 30th, 2023.
Definition / general
  • Usually young adults or children

Pott's disease:
  • Involvement of spine (thoracic / lumbar)
  • Extensive necrosis of intervertebral discs with extension into soft tissue
  • May produce significant deformities or neurologic deficits
  • Difficult to treat
Clinical features
  • In US, due to immigrants and immunosuppression
  • 1 - 3% with tuberculosis have bone infection, usually from focus of acute visceral disease, direct extension or lymphatics
  • Rarely causes inguinal mass with fluctuant psoas abscess
  • In AIDS patients, bone infection usually multifocal
  • Advanced cases are associated with cutaneous sinuses, which cause secondary bacterial infections
  • Associated with fusion of joint, denudation of cartilage, sequestra of medullary cavity
  • Can detect in synovial fluid by culture and examination
Sites
  • Vertebrae, hip, knee, ankle, elbow, wrist
  • Usually involves synovium, epiphysis or metaphysis
Radiology images

Contributed by Mark R. Wick, M.D.
Missing Image

Paraspinal tuberculous abscess MRI

Gross images

Contributed by Mark R. Wick, M.D.
Missing Image

Tubeculous vertebral osteomyelitis

Microscopic (histologic) images

Contributed by Mark R. Wick, M.D.
Missing Image

Various images

Differential diagnosis
Back to top
Image 01 Image 02