Bone & joints
Osteomyelitis
Tuberculous osteomyelitis


Topic Completed: 1 August 2013

Minor changes: 19 March 2021

Copyright: 2003-2021, PathologyOutlines.com, Inc.

PubMed Search: Tuberculous osteomyelitis[title]

Dariusz Borys, M.D.
Page views in 2020: 3,444
Page views in 2021 to date: 1,814
Cite this page: Borys D. Tuberculous osteomyelitis. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/boneTBosteo.html. Accessed June 12th, 2021.
Definition / general
  • Usually young adults or children

Pott's disease:
  • Involvement of spine (thoracic / lumbar)
  • Extensive necrosis of intervertebral discs with extension into soft tissue
  • May produce significant deformities or neurologic deficits
  • Difficult to treat
Clinical features
  • In US, due to immigrants and immunosuppression
  • 1 - 3% with tuberculosis have bone infection, usually from focus of acute visceral disease, direct extension or lymphatics
  • Rarely causes inguinal mass with fluctuant psoas abscess
  • In AIDS patients, bone infection usually multifocal
  • Advanced cases are associated with cutaneous sinuses, which cause secondary bacterial infections
  • Associated with fusion of joint, denudation of cartilage, sequestra of medullary cavity
  • Can detect in synovial fluid by culture and examination
Sites
  • Vertebrae, hip, knee, ankle, elbow, wrist
  • Usually involves synovium, epiphysis or metaphysis
Radiology images

Contributed by Mark R. Wick, M.D.
Missing Image

Cervical vertebrae
paraspinal tuberculous
abscess MRI

Gross images

Contributed by Mark R. Wick, M.D.
Missing Image

Tubeculous
vertebral
osteomyelitis
(Pott disease)

Microscopic (histologic) images

Contributed by Mark R. Wick, M.D.
Missing Image

Differential diagnosis
Back to top
Image 01 Image 02