Bone & joints
Osteosarcoma
Epithelioid osteosarcoma
Author: Nat Pernick, M.D.
Topic Completed: 1 August 2013
Minor changes: 8 January 2021
Revised: 28 December 2018
Copyright: (c) 2003-2018, PathologyOutlines.com, Inc.
PubMed Search: Epithelioid osteosarcoma
Table of Contents
Definition / general | Radiology description | Case reports | Microscopic (histologic) description | Additional referencesCite this page: Pernick N Epithelioid osteosarcoma. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/boneepithosteo.html. Accessed January 18th, 2021.
Definition / general
- Rare pattern with rosette-like configuration simulating glands
- Usually male patients under age 30
- Sites: metaphysis of long tubular bones
- Survival: poor, with 75% dead of multiple lung metastases despite surgery with wide margins and systemic chemotherapy; estimated 5 year survival of 15 (Hum Pathol 2001;32:726)
Radiology description
- Highly destructive with variable mineralization
Case reports
- 49 year old man with vertebral tumor (Arch Pathol Lab Med 1993;117:295)
Microscopic (histologic) description
- Osteoblastic osteosarcoma with small multinodular growth pattern, lacelike osteoid deposits, hemangiopericytoma-like vessels, rosette-like formation, epithelioid tumor cells
Additional references
