Bone marrow nonneoplastic

Alterations in cellularity

Bone marrow cellularity

Topic Completed: 1 December 2006

Revised: 7 January 2019

Copyright: (c) 2002-2019,, Inc.

PubMed Search: Bone marrow cellularity [title]

Nat Pernick, M.D.
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Table of Contents
Definition / general
Cite this page: Pernick N Bone marrow cellularity. website. Accessed December 3rd, 2021.
Definition / general
  • Best evaluated on biopsy sections or imprints; particle sections are next best choice
  • Aspirate smears may be difficult to evaluate but are accurate (Am J Hematol 1986;22:381, Indian J Pathol Microbiol 1989;32:186)
  • Theoretically could use automated hematology analyzer or flow cytometry (Ann Clin Lab Sci 2004;34:307)
  • Iliac crest may not be representative if radiotherapy or other local insults
  • Varies from 80% (children) to 55% (age 30) to < 50% (age 60+)
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