Bone & joints

Other tumors

Xanthoma



Topic Completed: 1 June 2005

Minor changes: 7 May 2021

Revised: 4 January 2019

Copyright: (c) 2003-2019, PathologyOutlines.com, Inc.

PubMed search: xanthoma [title] bone


Nat Pernick, M.D.
Page views in 2020: 583
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Cite this page: Pernick N Xanthoma. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/bonexanthoma.html. Accessed October 25th, 2021.
Definition / general
  • 65% male, age 20+ years
  • Usually solitary; affects pelvis, ribs, skull
Radiology description
  • Well defined, expansile lytic lesion, often with sclerotic margin
Microscopic (histologic) description
  • Foam cells, multinucleated giant cells, cholesterol clefts, fibrosis
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