CD Markers
CD114


Topic Completed: 1 August 2013

Minor changes: 9 October 2020

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PubMed Search: CD114[title]

Nat Pernick, M.D.
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Cite this page: Pernick N. CD114. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/cdmarkerscd114.html. Accessed January 16th, 2021.
Definition / general
  • Aka granulocyte colony-stimulating factor receptor, G-CSFR
  • Specific regulator of myeloid proliferation and differentiation
  • Mutations present in some patients with severe congenital neutropenia
Positive staining - normal
  • Granulocytes (all), monocytes, platelets, endothelium, placenta, trophoblastic cells
Positive staining - malignant
  • Cultured tumor cells
Negative staining
  • Eosinophils, lymphocytes, erythrocytes
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