CD Markers
CD121
Copyright: 2002-2021, PathologyOutlines.com, Inc.
PubMed Search: CD121a OR CDw121b
CD121
Author: Nat Pernick, M.D.
Topic Completed: 1 February 2002
Minor changes: 9 October 2020
Copyright: 2002-2021, PathologyOutlines.com, Inc.
PubMed Search: CD121a OR CDw121b
Cite this page: Pernick N. CD121. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/cdmarkerscd121.html. Accessed January 15th, 2021.
CD121a
Definition / general
Positive staining - normal
- Also known as Interleukin 1 receptor (IL-1R) type I, IL1-alpha
- Interleukin-1, an inflammatory mediator, consists of 2 separate but related proteins, IL1-alpha and IL1-beta
Positive staining - normal
- T cells, thymocytes, fibroblasts, endothelial cells
CDw121b
Definition / general
Positive staining - normal
- Also known as Interleukin 1 receptor (IL-1 R) type II, IL1-beta
- May inhibit IL1 activity by acting as a decoy target for IL1
Positive staining - normal
- B cells, macrophages
