CD Markers
CD126



Topic Completed: 1 February 2002

Minor changes: 9 October 2020

Copyright: 2002-2021, PathologyOutlines.com, Inc.

PubMed Search: CD126[title]

Nat Pernick, M.D.
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Cite this page: Pernick N. CD126. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/cdmarkerscd126.html. Accessed January 16th, 2021.
Definition / general
  • Aka Interleukin 6 receptor
  • Continuous expression of IL-6 and CD130, ligands for CD126, causes hypergammaglobulinemia, glomeruloproliferative nephritis and lymphoid infiltration in some organs
  • Dysregulated stimulation may cause myeloma and plasmacytoma
Positive staining - normal
  • T cells, monocytes, activated B cells, hepatocytes
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