Cite this page: Pernick N. CD126. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/cdmarkerscd126.html. Accessed January 16th, 2021.
Definition / general
- Aka Interleukin 6 receptor
- Continuous expression of IL-6 and CD130, ligands for CD126, causes hypergammaglobulinemia, glomeruloproliferative nephritis and lymphoid infiltration in some organs
- Dysregulated stimulation may cause myeloma and plasmacytoma
Positive staining - normal
- T cells, monocytes, activated B cells, hepatocytes