CD Markers
CD130
Copyright: 2002-2021, PathologyOutlines.com, Inc.
PubMed Search: CD130[title]
CD130
Author: Nat Pernick, M.D.
Topic Completed: 1 February 2002
Minor changes: 9 October 2020
Copyright: 2002-2021, PathologyOutlines.com, Inc.
PubMed Search: CD130[title]
Cite this page: Pernick N. CD130. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/cdmarkerscd130.html. Accessed January 16th, 2021.
Definition / general
- Aka gp 130
- Required for transducing biological activities of IL6, IL11, leukemia inhibitory factor, ciliary neurotrophic factor, oncostatin M, and cardiotrophin-1
- IL6 and oncostatin M dependent activation of gp130 are involved in multiple myeloma
Positive staining - normal
- Almost all cell types (low levels)
