CD Markers
CD130


Topic Completed: 1 February 2002

Minor changes: 9 October 2020

Copyright: 2002-2021, PathologyOutlines.com, Inc.

PubMed Search: CD130[title]

Nat Pernick, M.D.
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Cite this page: Pernick N. CD130. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/cdmarkerscd130.html. Accessed January 16th, 2021.
Definition / general
  • Aka gp 130
  • Required for transducing biological activities of IL6, IL11, leukemia inhibitory factor, ciliary neurotrophic factor, oncostatin M, and cardiotrophin-1
  • IL6 and oncostatin M dependent activation of gp130 are involved in multiple myeloma
Positive staining - normal
  • Almost all cell types (low levels)
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