CD Markers
CD132



Topic Completed: 1 February 2002

Minor changes: 9 October 2020

Copyright: 2002-2021, PathologyOutlines.com, Inc.

PubMed Search: CD132[title]

Nat Pernick, M.D.
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Cite this page: Pernick N. CD132. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/cdmarkerscd132.html. Accessed January 16th, 2021.
Definition / general
  • Aka common cytokine receptor gamma chain - receptor for IL-2, IL-4, IL-7, IL-9 and IL-15
  • Mutation in humans causes X-linked severe combined immunodeficiency (no T cells, no NK cells)
  • CD132 is a target molecule for gene therapy for X-SCID
Positive staining - normal
  • T cells, B cells, NK cells, monocytes/macrophages, neutrophils
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