CD Markers
CD15u


Topic Completed: 1 January 2014

Minor changes: 2 October 2020

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PubMed Search: sialyl 6-sulfo Lewis

Related topics: CD15, CD15s

Nat Pernick, M.D.
Page views in 2020: 42
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Cite this page: Pernick, N. CD15u. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/cdmarkerscd15u.html. Accessed January 16th, 2021.
Definition / general
  • Adhesion protein representing the sulfated form of CD15
  • Also called sialyl 6-sulfo Lewis
  • Major L-selectin ligand on high endothelial venules of human peripheral lymph nodes (Biochem Biophys Res Commun 2000;278:90)
Uses by pathologists
  • No significant clinical use by pathologists
Microscopic (histologic) images

Images hosted on other servers:

Colorectal cancer

Skin

Positive staining - normal
  • Neutrophils, basophils, mature granulocytes, monocytes, NK cells and T lymphocytes
  • Also immature bone marrow cells, endothelial cells of high endothelium (HEV) of peripheral lymph nodes
  • Expression on lymphocytes is variable depending on the antibodies used for detection
Positive staining - disease
  • Myelomonocytic leukemia cells, adenocarcinoma
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