CD Markers
CD15u
Copyright: 2003-2021, PathologyOutlines.com, Inc.
PubMed Search: sialyl 6-sulfo Lewis
Related topics: CD15, CD15s
CD15u
Author: Nat Pernick, M.D.
Topic Completed: 1 January 2014
Minor changes: 2 October 2020
Copyright: 2003-2021, PathologyOutlines.com, Inc.
PubMed Search: sialyl 6-sulfo Lewis
Related topics: CD15, CD15s
Table of Contents
Definition / general | Uses by pathologists | Microscopic (histologic) images | Positive staining - normal | Positive staining - diseaseCite this page: Pernick, N. CD15u. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/cdmarkerscd15u.html. Accessed January 16th, 2021.
Definition / general
- Adhesion protein representing the sulfated form of CD15
- Also called sialyl 6-sulfo Lewis
- Major L-selectin ligand on high endothelial venules of human peripheral lymph nodes (Biochem Biophys Res Commun 2000;278:90)
Uses by pathologists
- No significant clinical use by pathologists
Microscopic (histologic) images
Images hosted on other servers:
Colorectal cancer
Skin
Positive staining - normal
- Neutrophils, basophils, mature granulocytes, monocytes, NK cells and T lymphocytes
- Also immature bone marrow cells, endothelial cells of high endothelium (HEV) of peripheral lymph nodes
- Expression on lymphocytes is variable depending on the antibodies used for detection
Positive staining - disease
- Myelomonocytic leukemia cells, adenocarcinoma
