CD Markers
CD179
Copyright: 2002-2021, PathologyOutlines.com, Inc.
CD179
Author: Nat Pernick, M.D.
Topic Completed: 1 February 2002
Minor changes: 12 November 2020
Copyright: 2002-2021, PathologyOutlines.com, Inc.
Cite this page: Pernick N. CD179. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/cdmarkerscd179.html. Accessed January 15th, 2021.
Definition / general
- CD179a:
- Aka VpreB1
- Associates non-covalently with CD179b to form surrogate light chain as component of preB cell receptor, which plays a critical role in early B cell differentiation
- CD179b:
- Aka lambda-5
- Associates non-covalently with CD179a to form surrogate light chain as component of preB cell receptor, which plays a critical role in early B cell differentiation
- Mutations impair B cell development and cause agammaglobulinemia
Positive staining - normal
- PreB cells
