Cite this page: Pernick N. CD184. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/cdmarkerscd184.html. Accessed July 31st, 2021.
Definition / general
- Aka CXCR4, Stromal cell Derived Factor 1 (SDF1)
- Receptor for the CXC chemokine SDF-1
- Also major HIV/SIV co-receptor (with CCR5/CD195)
- Involved in B cell development, myelopoiesis, cardiac ventricular septum formation, blood vessel formation in GI tract, cerebellar granular cell development
Positive staining - normal
- All mature blood cells, blood progenitor cells, endothelial and epithelial cells, astrocytes, neurons