CD Markers
CD184 / CXCR4
Copyright: 2002-2023, PathologyOutlines.com, Inc.
PubMed Search: CD184
See Also: Molecular markers - CXCR4
CD184 / CXCR4
Author: Nat Pernick, M.D.
Last author update: 1 February 2002
Last staff update: 29 March 2023
Copyright: 2002-2023, PathologyOutlines.com, Inc.
PubMed Search: CD184
See Also: Molecular markers - CXCR4
Cite this page: Pernick N. CD184 / CXCR4. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/cdmarkerscd184.html. Accessed June 3rd, 2023.
Definition / general
- Aka CXCR4, Stromal cell Derived Factor 1 (SDF1)
- Receptor for the CXC chemokine SDF-1
- Also major HIV/SIV co-receptor (with CCR5/CD195)
- Involved in B cell development, myelopoiesis, cardiac ventricular septum formation, blood vessel formation in GI tract, cerebellar granular cell development
Positive staining - normal
- All mature blood cells, blood progenitor cells, endothelial and epithelial cells, astrocytes, neurons
