CD Markers
CD184


Topic Completed: 1 February 2002

Minor changes: 14 May 2021

Copyright: 2002-2021, PathologyOutlines.com, Inc.

PubMed Search: CD184


Nat Pernick, M.D.
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Cite this page: Pernick N. CD184. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/cdmarkerscd184.html. Accessed July 31st, 2021.
Definition / general
  • Aka CXCR4, Stromal cell Derived Factor 1 (SDF1)
  • Receptor for the CXC chemokine SDF-1
  • Also major HIV/SIV co-receptor (with CCR5/CD195)
  • Involved in B cell development, myelopoiesis, cardiac ventricular septum formation, blood vessel formation in GI tract, cerebellar granular cell development
Positive staining - normal
  • All mature blood cells, blood progenitor cells, endothelial and epithelial cells, astrocytes, neurons
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