CD Markers
CD201


Topic Completed: 1 August 2013

Minor changes: 13 November 2020

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PubMed Search: CD201

Nat Pernick, M.D.
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Cite this page: Pernick N. CD201. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/cdmarkerscd201.html. Accessed January 16th, 2021.
Definition / general
  • Binds protein C in a calcium-dependent manner
  • Aka Endothelial Protein C Receptor (EPC R), protein C receptor
  • Protein C is a vitamin K dependent enzyme with major role in coagulation of blood; activated when thrombin binds to thrombomodulin on endothelium.
  • Mutations in CD201 and thrombomodulin associated with late fetal loss; similar mutation associated with venous thromboembolism and myocardial infarction
Positive staining - normal
  • Endothelial cells (not in liver and kidney)
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