CD Markers
CD202b
Copyright: 2003-2021, PathologyOutlines.com, Inc.
PubMed Search: CD202b
CD202b
Author: Nat Pernick, M.D.
Topic Completed: 1 August 2013
Minor changes: 13 November 2020
Copyright: 2003-2021, PathologyOutlines.com, Inc.
PubMed Search: CD202b
Cite this page: Pernick N. CD202b. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/cdmarkerscd202.html. Accessed January 15th, 2021.
Definition / general
- Aka Tie2 (Tyrosine kinase with Ig-like loops and Epidermal growth factor homology domains), aka Tek
- Receptor tyrosine kinase at #9p21, binds to angiopoietin-1
- May be earliest mammalian endothelial cell lineage marker
- Involved in vein morphogenesis and communication between endothelial and smooth muscle cells for remodeling and repair of blood vessels
- Defects associated with inherited venous malformations
Positive staining - normal
- Endothelial cells, hematopoietic cells
