CD Markers

Topic Completed: 1 August 2013

Minor changes: 13 November 2020

Copyright: 2003-2021,, Inc.

PubMed Search: CD202b

Nat Pernick, M.D.
Page views in 2020: 25
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Cite this page: Pernick N. CD202b. website. Accessed January 15th, 2021.
Definition / general
  • Aka Tie2 (Tyrosine kinase with Ig-like loops and Epidermal growth factor homology domains), aka Tek
  • Receptor tyrosine kinase at #9p21, binds to angiopoietin-1
  • May be earliest mammalian endothelial cell lineage marker
  • Involved in vein morphogenesis and communication between endothelial and smooth muscle cells for remodeling and repair of blood vessels
  • Defects associated with inherited venous malformations
Positive staining - normal
  • Endothelial cells, hematopoietic cells
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