Cite this page: Pernick N. CDw210-219. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/cdmarkerscd210.html. Accessed December 4th, 2024.
CDw210
- Aka IL-10 receptor
- Interleukin-10 (OMIM 124092) produced by B cells, T helper cells, and monocyte/macrophages, exhibits diverse activities on different cell lines
- IL10 inhibits macrophage activation by interferon-gamma
- Positive staining - normal:
CD211
- CD Marker not assigned to a set of antibodies as of 20 December 2011
CD212
- Aka IL-12 receptor
- Interleukin-12 promotes cell-mediated immunity to intracellular pathogens by inducing type 1 helper T cell responses and interferon-gamma production
- Lack of IL12 associated with severe, idiopathic mycobacterial and Salmonella infections, mature granulomas
- Positive staining - normal: T cells, NK cells
CD213
- CD213a1:
- Aka IL13 receptor, alpha 1
- Binds IL13 with low affinity
- With IL4r-alpha, can form a functional receptor for IL13
- Positive staining - normal: ubiquitous, B cells, T cells and endothelial cells, highest levels in heart, liver, skeletal muscle and ovary
- CD213a2:
- Aka IL13 receptor, alpha 2
- Inhibits binding of interleukin 13 to the IL13 cell surface receptor
- Positive staining - normal: placenta
CD214
- No information available
CD215
- CD Marker not assigned to a set of antibodies as of 20 December 2011
CD216
- CD Marker not assigned to a set of antibodies as of 20 December 2011
CDw217
CD218
- No information available
CD219
- CD Marker not assigned to a set of antibodies as of 20 December 2011