CD Markers
CDw210-219


Topic Completed: 1 August 2013

Minor changes: 14 May 2021

Copyright: 2003-2021, PathologyOutlines.com, Inc.

PubMed Search: CDw210

Nat Pernick, M.D.
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Page views in 2021 to date: 41
Table of Contents
CDw210 | CD211 | CD212 | CD213 | CD214 | CD215 | CD216 | CDw217 | CD218 | CD219
Cite this page: Pernick N. CDw210-219. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/cdmarkerscd210.html. Accessed June 23rd, 2021.
CDw210
  • Aka IL-10 receptor
  • Interleukin-10 (OMIM 124092) produced by B cells, T helper cells, and monocyte/macrophages, exhibits diverse activities on different cell lines
  • IL10 inhibits macrophage activation by interferon-gamma
  • Positive staining - normal:
CD211
  • CD Marker not assigned to a set of antibodies as of 20 December 2011
CD212
  • Aka IL-12 receptor
  • Interleukin-12 promotes cell-mediated immunity to intracellular pathogens by inducing type 1 helper T cell responses and interferon-gamma production
  • Lack of IL12 associated with severe, idiopathic mycobacterial and Salmonella infections, mature granulomas
  • Positive staining - normal: T cells, NK cells
CD213
  • CD213a1:
    • Aka IL13 receptor, alpha 1
    • Binds IL13 with low affinity
    • With IL4r-alpha, can form a functional receptor for IL13
    • Positive staining - normal: ubiquitous, B cells, T cells and endothelial cells, highest levels in heart, liver, skeletal muscle and ovary
  • CD213a2:
    • Aka IL13 receptor, alpha 2
    • Inhibits binding of interleukin 13 to the IL13 cell surface receptor
    • Positive staining - normal: placenta
CD214
  • No information available
CD215
  • CD Marker not assigned to a set of antibodies as of 20 December 2011
CD216
  • CD Marker not assigned to a set of antibodies as of 20 December 2011
CDw217
  • Aka IL 17 receptor
  • Cytokine that is induced in activated CD4+ T cells
  • IL17 induces stromal cells to produce proinflammatory and hematopoietic cytokines; enhances expression in fibroblasts of ICAM-1
CD218
  • No information available
CD219
  • CD Marker not assigned to a set of antibodies as of 20 December 2011
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