CD Markers

Topic Completed: 1 August 2013

Minor changes: 13 November 2020

Copyright: 2003-2021,, Inc.

PubMed Search: Fy glycoprotein

Nat Pernick, M.D.
Page views in 2020: 34
Cite this page: Pernick N. CD234. website. Accessed January 15th, 2021.
Definition / general
  • Aka Duffy blood group antigen (Fy glycoprotein); erythrocyte chemokine receptor, Duffy Antigen Receptor for Chemokines (DARC)
  • RBC receptor for Plasmodium vivax, a malarial parasite
  • Negativity associated with sickle cell trait, due to common protection against malaria provided by both traits African-Americans often Duffy negative and resistant to P. vivax malaria
Positive staining - normal
  • Endothelial cells of postcapillary venules, Purkinje cells of cerebellum
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