CD Markers
CD241
Copyright: 2002-2021, PathologyOutlines.com, Inc.
PubMed Search: RH50 glycoprotein or RHAG or Rhesus blood group associated glycoprotein
CD241
Author: Nat Pernick, M.D.
Topic Completed: 1 February 2002
Minor changes: 16 November 2020
Copyright: 2002-2021, PathologyOutlines.com, Inc.
PubMed Search: RH50 glycoprotein or RHAG or Rhesus blood group associated glycoprotein
Table of Contents
Definition / general | Uses by pathologists | Positive staining - normal | Additional referencesCite this page: Pernick N. CD241. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/cdmarkerscd241.html. Accessed January 15th, 2021.
Definition / general
- Also called RH50 glycoprotein, RHAG, Rhesus blood group associated glycoprotein
- Located at #6p21.1-p11
- Is a strictly required posttranscriptional factor regulating Rh membrane expression (Blood 2002;100:1038)
- Also appears to be an ammonium transporter (Proc Natl Acad Sci USA 2004;101:17222) and a CO2 channel (FASEB J 2008;22:64)
- Defects cause Rh-null phenotype (OMIM 268150), associated with a chronic hemolytic anemia and spherostomatocytosis (J Biol Chem 1998;273:2207)
Uses by pathologists
- Blood typing
Positive staining - normal
- Erythroid cells
Additional references
