CD Markers
CD245
Copyright: 2002-2021, PathologyOutlines.com, Inc.
PubMed Search: p220 or p240 [title]
CD245
Author: Nat Pernick, M.D.
Topic Completed: 1 February 2002
Minor changes: 16 November 2020
Copyright: 2002-2021, PathologyOutlines.com, Inc.
PubMed Search: p220 or p240 [title]
Cite this page: Pernick N. CD245. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/cdmarkerscd245.html. Accessed January 15th, 2021.
Definition / general
- Also called p220/240
- Very little information is available for CD245 directly; appears to be identical to NPAT (nuclear protein, ataxia-telangiectasia locus)
- NPAT links S phase cyclin E/Cdk2 kinase activity to replication-dependent histone gene transcription (Biochemistry 2006;45:15915, Mol Cell Biol 2005;25:6140)
Uses by pathologists
- No significant clinical use by pathologists
Positive staining - normal
- T cells (some), other white blood cells with varying intensity (Washington State Univ)
