CD Markers
CD249
Copyright: 2002-2021, PathologyOutlines.com, Inc.
PubMed Search: ENPEP or glutamyl aminopeptidase or aminopeptidase A
CD249
Author: Nat Pernick, M.D.
Topic Completed: 1 December 2014
Minor changes: 16 November 2020
Copyright: 2002-2021, PathologyOutlines.com, Inc.
PubMed Search: ENPEP or glutamyl aminopeptidase or aminopeptidase A
Table of Contents
Definition / general | Uses by pathologists | Positive staining - normal | Positive staining - disease | Additional referencesCite this page: Pernick N. CD249. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/cdmarkerscd249.html. Accessed January 15th, 2021.
Definition / general
- Also called ENPEP, glutamyl aminopeptidase, differentiation antigen gp160, aminopeptidase A
- Regulates blood pressure via renin-angiotensin system (J Biol Chem 2006;281:23503)
Uses by pathologists
- No significant clinical use by pathologists
Positive staining - normal
- Kidney; also brain, heart, liver, lung, placenta, skeletal muscle, pancreas (Genomics 1993;17:657)
Positive staining - disease
- Cervical neoplasia (Lab Invest 2004;84:639), renal cell carcinoma-some (Proc Natl Acad Sci USA 1993;90:7069)
Additional references
