CD Markers
CD44R


Topic Completed: 1 October 2013

Minor changes: 18 October 2021

Copyright: 2003-2022, PathologyOutlines.com, Inc.

PubMed Search: CD44v, CD44v9

Nat Pernick, M.D.
Page views in 2021: 97
Page views in 2022 to date: 6
Cite this page: Pernick N. CD44R. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/cdmarkerscd44r.html. Accessed January 21st, 2022.
Definition / general
  • Heterogeneous group of CD44 variant isoforms expressed constitutively in epithelial cells and monocyte lineage cells; upregulated in activated leukocytes
  • Also called CD44v, CD44v9
  • See CD44 for more information
Pathophysiology
  • Transcripts for CD44 undergo complex alternative splicing, causing functionally distinct isoforms, whose nature has not yet been determined
  • Cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration
Uses by pathologists
  • No significant clinical uses for pathologists
Positive staining - disease
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