CD Markers

Topic Completed: 1 December 2010

Minor changes: 18 September 2020

Copyright: 2002-2021,, Inc.

PubMed Search: CD49e[TIAB] pathology "full text"[SB]

Nat Pernick, M.D.
Page views in 2020: 6
Page views in 2021 to date: 5
Cite this page: Pernick N. CD49e. website. Accessed January 15th, 2021.
Definition / general
  • Fibronectin and fibrinogen receptor
  • Also called very late antigen (VLA) alpha 5 chain (VLA5), ITGA5, fibronectin receptor (FNRA)
  • Recognizes the sequence R-G-D in fibronectin and fibrinogen, mediating its adhesion function
Clinical features
Uses by pathologists
  • No significant clinical use by pathologists
Immunofluorescence images

Contributed by Dr. Vincent Achard
Peripheral blood monocytes and platelets (green is positive)

Peripheral blood monocytes and platelets (green is positive)

Negative control

Negative control

Positive staining - normal
  • T cells, early and activated B cells, platelets, monocytes, neutrophils
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