CD Markers
CD65s
Copyright: 2002-2021, PathologyOutlines.com, Inc.
PubMed Search: CD65s
CD65s
Author: Nat Pernick, M.D.
Topic Completed: 1 February 2002
Minor changes: 2 October 2020
Copyright: 2002-2021, PathologyOutlines.com, Inc.
PubMed Search: CD65s
Table of Contents
Definition / general | Uses by pathologists | Positive staining - normal | Positive staining - diseaseCite this page: Pernick N. CD65s. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/cdmarkerscd65s.html. Accessed January 16th, 2021.
Definition / general
- Also called sialylated-CD65
- A carbohydrate antigen, not a protein
- Appears when CD34 antigen disappears
- Antibodies may either recognize CD65s (sialylated) or CD65 (non-sialylated)
Uses by pathologists
- For acute leukemia cell typing and to identify a subset of pre-pre-B ALL (Am J Clin Pathol 2002;117:380)
Positive staining - normal
- Granulocytes, monocytes
Positive staining - disease
- Myeloid leukemia, low levels in AML M0-M1 (Leukemia 2003;17:1544)
