CD Markers
CD66


Topic Completed: 1 November 2014

Minor changes: 8 October 2020

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PubMed Search: CD66

Nat Pernick, M.D.
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Cite this page: Pernick N. CD66. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/cdmarkerscd66.html. Accessed April 15th, 2021.
Definition / general
Uses by pathologists
Microscopic (histologic) images

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Colon

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Expression at maternal-fetal surface

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Various breast lesions (Figure 1)

Positive staining - normal
  • Granulocytes, lymphocytes, epithelial cells, endothelial cells, prostate glands and ducts (dense), bile canaliculi between liver cells, extravillous trophoblast (Am J Pathol 2000;156:1165)
Positive staining - disease
  • Low grade prostate carcinoma
Negative staining
  • High grade (Gleason 4/5) prostate carcinoma
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