CD Markers
CD66b (formerly CD67)
Copyright: 2003-2021, PathologyOutlines.com, Inc.
PubMed Search: CD66b
CD66b (formerly CD67)
Author: Nat Pernick, M.D.
Topic Completed: 1 November 2014
Minor changes: 8 October 2020
Copyright: 2003-2021, PathologyOutlines.com, Inc.
PubMed Search: CD66b
Table of Contents
Definition / general | Uses by pathologists | Positive staining - normal | Positive staining - diseaseCite this page: Pernick N. CD66b. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/cdmarkerscd66b.html. Accessed January 16th, 2021.
Definition / general
- Also called CEACAM8. NCA-95 and CGM6; formerly CD67
- Cell adhesion molecule capable of activating neutrophils
- Increased expression on peripheral blood neutrophils and eosinophils of rheumatoid arthritis patients (Scand J Immunol 1999;50:433)
Uses by pathologists
- Marker for granulocytes
Positive staining - normal
- Granulocytes
Positive staining - disease
- Chronic myelogenous leukemia (Cancer Res 1990;50:6534), cardiomyocytes in areas of infarction (Cardiovasc Res 1999;41:603)
