CD Markers
CD66d
Copyright: 2003-2019, PathologyOutlines.com, Inc.
PubMed Search: CD66d
CD66d
Author: Nat Pernick, M.D.
Topic Completed: 1 November 2014
Minor changes: 23 October 2019
Copyright: 2003-2019, PathologyOutlines.com, Inc.
PubMed Search: CD66d
Cite this page: Pernick N. CD66d. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/cdmarkerscd66d.html. Accessed August 10th, 2020.
Definition / general
- Also called CEACAM3, CGM1
- Cell adhesion molecule capable of activating neutrophils
- Has important role in control of pathogens by the innate (opsonin-independent) immune system (J Exp Med 2004;199:35)
- Used by Neisseria. gonorrhoeae, Moraxella catarrhalis and Hemophilus influenzae to anchor themselves to and invade host cells
- N. gonorrheae has an opacity-associated (Opa) protein that binds to CEACAM3 (J Biol Chem 2001;276:17413)
- References: OMIM #609142
Uses by pathologists
- No significant clinical use by pathologists
Positive staining - normal
- Granulocytes
