CD Markers

Topic Completed: 1 November 2014

Minor changes: 8 October 2020

Copyright: 2003-2021,, Inc.

PubMed Search: CD66d

Nat Pernick, M.D.
Page views in 2020: 19
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Cite this page: Pernick N. CD66d. website. Accessed January 16th, 2021.
Definition / general
  • Also called CEACAM3, CGM1
  • Cell adhesion molecule capable of activating neutrophils
  • Has important role in control of pathogens by the innate (opsonin-independent) immune system (J Exp Med 2004;199:35)
  • Used by Neisseria. gonorrhoeae, Moraxella catarrhalis and Hemophilus influenzae to anchor themselves to and invade host cells
  • N. gonorrheae has an opacity-associated (Opa) protein that binds to CEACAM3 (J Biol Chem 2001;276:17413)
  • References: OMIM #609142
Uses by pathologists
  • No significant clinical use by pathologists
Positive staining - normal
  • Granulocytes
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