Table of Contents
Definition / general | Uses by pathologists | Microscopic (histologic) images | Positive staining - normal | Positive staining - diseaseCite this page: Pernick N. CD66f. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/cdmarkerscd66f.html. Accessed January 16th, 2021.
Definition / general
- Also called pregnancy-specific beta-1 glycoprotein, PSG1
- May be involved in immune regulation, protection of fetus from maternal immune system
- Released into maternal circulation during pregnancy
- Low levels in maternal blood predict spontaneous abortion
- References: OMIM #176390
Uses by pathologists
- No significant clinical use by pathologists
Microscopic (histologic) images
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Positive staining - normal
- Syncytiotrophoblasts, fetal liver and myeloid cells
Positive staining - disease
- Hydatidiform and invasive moles, choriocarcinoma (J Clin Pathol 1977;30:19)