CD Markers
CD84
Copyright: 2002-2021, PathologyOutlines.com, Inc.
PubMed Search: CD84
CD84
Author: Nat Pernick, M.D.
Topic Completed: 1 February 2002
Minor changes: 9 October 2020
Copyright: 2002-2021, PathologyOutlines.com, Inc.
PubMed Search: CD84
Cite this page: Pernick N. CD84. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/cdmarkerscd84.html. Accessed January 15th, 2021.
Definition / general
- Also called Signaling Lymphocytic Activation Molecule 5 (SLAM5)
- Adhesion molecule that increases proliferative responses of activated T cells (J Immunol 2003;171:2485)
- Mediates platelet aggregation (Blood 2005;106:3028)
- References: OMIM #604513
Uses by pathologists
- No significant clinical use by pathologists
Positive staining - normal
- B cells, thymocytes (J Immunol 2001;167:3668), mature T cells, memory T cells (high, Tissue Antigens 2004;64:132), monocytes / macrophages, platelets, dendritic cells, granulocytes and CD34+ hematopoietic progenitor cells (Exp Hematol 2003;31:798)
