CD Markers
CD90
Copyright: 2002-2021, PathologyOutlines.com, Inc.
PubMed Search: CD90[title]
CD90
Author: Nat Pernick, M.D.
Topic Completed: 1 February 2002
Minor changes: 9 October 2020
Copyright: 2002-2021, PathologyOutlines.com, Inc.
PubMed Search: CD90[title]
Table of Contents
Definition / general | Uses by pathologists | Microscopic (histologic) images | Positive staining - normal | Negative staining - diseaseCite this page: Pernick N. CD90. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/cdmarkerscd90.html. Accessed January 15th, 2021.
Definition / general
- Also called Thy-1
- May mediate differentiation of hematopoietic stem cells and synaptogenesis in the CNS
- CD34+ CD90+ cells include hematopoietic stem cells that serve as autologous grafts to replace the bone marrow in patients with malignancies (Biol Blood Marrow Transplant 2000;6:262)
- Mediates adhesion of various white blood cells to activated endothelial cells (J Immunol 2004;172:3850)
Uses by pathologists
- Hematopoietic stem cell marker
Microscopic (histologic) images
Images hosted on other servers:
Normal and diseased skin
Positive staining - normal
- Immature hematopoietic stem cells, neurons, connective tissue, activated endothelial cells, fibroblasts (variable, Am J Pathol 2003;163:1291), keratinocyte stem cells (Br J Dermatol 2006;154:1062)
Negative staining - disease
- Ewing sarcoma and some rhabdomyosarcomas (Am J Clin Pathol 2003;119:643)
