CD Markers
CD98
Copyright: 2003-2021, PathologyOutlines.com, Inc.
PubMed Search: CD98[title]
CD98
Author: Nat Pernick, M.D.
Topic Completed: 1 September 2013
Minor changes: 9 October 2020
Copyright: 2003-2021, PathologyOutlines.com, Inc.
PubMed Search: CD98[title]
Table of Contents
Definition / general | Uses by pathologists | Microscopic (histologic) images | Positive staining - normal | Positive staining - malignant | Additional referencesCite this page: Pernick N. CD98. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/cdmarkerscd98.html. Accessed January 16th, 2021.
Definition / general
- Also called SLC3A2
- Heavy chain of amino acid transporters (J Cell Sci 2005;118:889)
- Involved in cell fusion necessary for syncytiotrophoblast formation (J Physiol 2003;550:3)
- Strongly expressed by neoplastic cells; expression contributes to transformation by promoting anchorage and serum independent growth (J Biol Chem 2004;279:54731)
Uses by pathologists
- No significant clinical use by pathologists
Microscopic (histologic) images
Images hosted on other servers:
Placenta (fig 4)
Positive staining - normal
- Broad
Positive staining - malignant
- All tumor cells
Additional references
