Premalignant / preinvasive lesions - cytology

Atypical repair (cyto)

Topic Completed: 3 June 2002

Minor changes: 6 July 2020

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PubMed search: cervix cytology atypical repair

Marilin Rosa, M.D.
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Cite this page: Rosa M. Atypical repair (cyto). PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/cervixcytologyatypicalrepair.html. Accessed September 20th, 2021.
Definition / general
Cytology description
  • Few cohesive tissue fragments, uniform nuclei, chromatin with increased chromatin granules, hyperchromasia, prominent nucleoli, scarce mitotic activity
  • Liquid based cytology: scattered atypical squamous cells with prominent nucleoli and other evidence of reparative change; also more obvious nuclear pleomorphism, anisonucleosis, nuclear outline irregularities, coarsening of chromatin and focal loss of nuclear polarity (Cancer 2003;99:141)
Differential diagnosis
  • Poorly differentiated squamous cell carcinoma or adenocarcinoma
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