Cervix
Inflammation / parasites
Granulomas


Topic Completed: 1 November 2010

Minor changes: 26 March 2020

Copyright: 2006-2020, PathologyOutlines.com, Inc.

PubMed search: Cervix granuloma

Farnaz Hasteh, M.D.
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Cite this page: Hasteh F. Granulomas. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/cervixgranulomas.html. Accessed May 26th, 2020.
Definition / general
  • Chronic inflammation with epithelioid histiocytes, giant cells and lymphocytes
  • Rare
  • Usually foreign body type; also diffuse
  • Associated with prior biopsy or surgery (Am J Clin Pathol 2002;117:771)
  • Only rarely associated with sarcoidosis or systemic conditions
  • Ceroid (with early lipofuscin) granulomas may be related to endometriosis (J Clin Pathol 1995;48:1057)
Terminology
  • Also called granulomatous cervicititis
Epidemiology
  • Uncommon
Etiology
  • Tuberculosis, amebiasis, schistosomiasis, brucellosis, tularemia, sarcoidosis and noninfectious causes like foreign body reaction to sutures (Diagn Cytopathol 1995;13:336)
  • Also post radiation
Case reports
Microscopic (histologic) description
  • Collection of epithelioid histiocytes or granuloma
Microscopic (histologic) images

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Xanthogranuloma (ceroid granuloma)

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PAS+

Cytology description
  • Inflammatory reaction, foreign body giant cells, phagocytosed refractile suture material (in some cases)
  • Granuloma rarely seen in Pap test (tuberuclosis)
Differential diagnosis
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