Mesenchymal / mixed epithelial & mesenchymal tumors

Papillary adenofibroma

Topic Completed: 1 May 2007

Minor changes: 12 March 2020

Copyright: 2007-2021, PathologyOutlines.com, Inc.

PubMed Search: Papillary adenofibroma cervix

Branko Perunovic, D.M.
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Cite this page: Perunovic B. Papillary adenofibroma. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/cervixpapillaryadenofibroma.html. Accessed December 3rd, 2021.
Definition / general
  • Uncommon in cervix, more common in endometrium
  • Usually postmenopausal women
Case reports
Gross description
  • Protrudes into endocervical canal
  • Papillary or sessile, may be 5 cm or larger
  • Firm, rubbery, tan brown with focal hemorrhage
  • May have small cysts on cut surface
  • No invasion of underlying stroma
Microscopic (histologic) description
  • Lobulated papillary configuration
  • Blunt edged and branching papillae covered by bland endocervical epithelium with stromal proliferation
  • May have focal squamous differentiation
  • Stromal cells are small, uniform, bland
  • No / rare mitotic figures
  • No increased cellularity around entrapped glands
Differential diagnosis
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