Benign / nonneoplastic epithelial lesions

Pseudosarcomatous fibroepithelial stromal polyps

Topic Completed: 1 May 2007

Minor changes: 18 February 2021

Copyright: 2007-2021, PathologyOutlines.com, Inc.

PubMed Search: Pseudosarcomatous fibroepithelial stromal polyp

Branko Perunovic, D.M.
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Cite this page: Perunovic, B. Pseudosarcomatous fibroepithelial stromal polyps. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/cervixpseudosarcomatous.html. Accessed December 3rd, 2021.
Definition / general
  • Median age 32 years, range 16 to 75 years
  • Often in pregnant patients or postoperative
  • May recur locally; no metastases
  • Positive margin status, which is common, apparently is not associated with recurrence
Gross description
  • Often multiple lesions, particularly in pregnant women
  • Tender, skin-colored, sac-like
Microscopic (histologic) description
  • Resemble fibroepithelial stromal polyps of vagina and vulva, but with bizarre morphology, frequent mitoses (>10/10 HPF), atypical mitotic figures or hypercellularity
  • Clues to diagnosis are characteristic stellate cells and multinucleate stromal cells, and extension of lesions up to mucosal-submucosal interface
Positive stains
Differential diagnosis
Additional references
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