Squamous cell carcinoma

Spindle cell carcinoma

Topic Completed: 1 May 2007

Minor changes: 20 November 2020

Copyright: 2007-2021, PathologyOutlines.com, Inc.

PubMed Search: Spindle cell carcinoma cervix

Branko Perunovic, D.M.
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Cite this page: Perunovic B. Spindle cell carcinoma. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/cervixspindlecell.html. Accessed December 3rd, 2021.
Definition / general
  • Also called sarcomatoid carcinoma
  • Similar to upper aerodigestive tract counterpart
  • Mean age 48 years, range 29 - 76 years
  • Aggressive; tumors often recur and cause death (Gynecol Oncol 2003;90:23)
Case reports
Microscopic (histologic) description
  • Poorly differentiated squamous cell carcinoma with spindle shaped cells
  • Often osteoclast - like giant cells
Positive stains
Differential diagnosis
  • MMMT: spindle cell component is malignant
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