Cervix
Other tumors
Yolk sac tumor
Author: Branko Perunovic, D.M.
Topic Completed: 1 May 2007
Minor changes: 30 November 2020
Copyright: 2007-2021, PathologyOutlines.com, Inc.
PubMed Search: Yolk sac tumor cervix
Table of Contents
Definition / general | Case reports | Treatment | Gross description | Microscopic (histologic) description | Microscopic (histologic) imagesCite this page: Perunovic B. Yolk sac tumor. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/cervixyst.html. Accessed January 22nd, 2021.
Definition / general
- Also called endodermal sinus tumor
- More common in vagina; some arise in both areas
- Usually girls 1 - 2 years old with blood-tinged vaginal discharge and variably elevated serum alpha - fetoprotei
Case reports
- 6 month old girl with tumor of vagina and cervix (Pediatr Radiol 1993;23:57)
- Patient with endodermal sinus tumor of cervix (Indian J Cancer 1996;33:43)
Treatment
- Surgery and chemotherapy
Gross description
- Partially eroded, pedunculated, soft and friable
Microscopic (histologic) description
- Reticular (net - like), solid and festoon (string or garland) patterns are most common
- Usually Schiller - Duval bodies (central blood vessel surrounded by primitive cells)
Microscopic (histologic) images
AFIP images
Microcystic pattern
Festoon pattern with Schiller - Duval bodies
