Other tumors

Yolk sac tumor

Topic Completed: 1 May 2007

Minor changes: 30 November 2020

Copyright: 2007-2021, PathologyOutlines.com, Inc.

PubMed Search: Yolk sac tumor cervix

Branko Perunovic, D.M.
Page views in 2020: 345
Page views in 2021 to date: 305
Cite this page: Perunovic B. Yolk sac tumor. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/cervixyst.html. Accessed December 3rd, 2021.
Definition / general
  • Also called endodermal sinus tumor
  • More common in vagina; some arise in both areas
  • Usually girls 1 - 2 years old with blood-tinged vaginal discharge and variably elevated serum alpha - fetoprotei
Case reports
  • Surgery and chemotherapy
Gross description
  • Partially eroded, pedunculated, soft and friable
Microscopic (histologic) description
  • Reticular (net - like), solid and festoon (string or garland) patterns are most common
  • Usually Schiller - Duval bodies (central blood vessel surrounded by primitive cells)
Microscopic (histologic) images

AFIP images

Microcystic pattern

Festoon pattern with Schiller - Duval bodies

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