CNS & pituitary tumors

Pineal tumors

Pineal parenchymal tumor of intermediate differentiation



Last author update: 1 January 2006
Last staff update: 18 August 2020

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PubMed Search: Pineal parenchymal tumor of intermediate differentiation

Nat Pernick, M.D.
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Cite this page: Pernick N. Pineal parenchymal tumor of intermediate differentiation. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/cnstumorpinealparenchymalintermediate.html. Accessed March 29th, 2024.
Definition / general
  • Features intermediate between pineocytoma and pineoblastoma
  • 10% of pineal parenchymal tumors
  • Occasionally associated with CNS or extraneural metastasis but otherwise difficult to predict prognosis
  • Better survival than pineoblastoma
Microscopic (histologic) description
  • Marked hypercellularity but relatively bland nuclear features
  • No / mild nuclear pleomorphism
  • No / rare pinocytomatous rosettes
  • Minimal mitotic activity
Molecular / cytogenetics description
Additional references
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