CNS & pituitary tumors
Pineal tumors
Pineocytoma
Author: Nat Pernick, M.D.
Last author update: 1 January 2006
Last staff update: 2 October 2024 (update in progress)
Copyright: 2002-2024, PathologyOutlines.com, Inc.
PubMed Search: Pineocytoma [title]
Table of Contents
Definition / general | Gross description | Microscopic (histologic) description | Differential diagnosisCite this page: Pernick N. Pineocytoma. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/cnstumorpineocytoma.html. Accessed December 4th, 2024.
Definition / general
- Grade 1 of 4
- Mostly adults age 25 - 35 years
- Slow growing
- Average survival 7 years
Gross description
- Well circumscribed, gray, hemorrhagic
Microscopic (histologic) description
- Similar to normal pineal glands well differentiated cells but hypercellular
- Fibrovascular stroma highlights expansive lobules of tumor cells with uniform round nuclei
- Pinocytomatous rosettes (large, loose, Homer Wright-like rosettes with central fibrillar zones surrounded by neoplastic cells with round nuclei)
- May have features of neuronal differentiation (ganglion cells)
- Noninfiltrative, no / rare mitotic figures, no necrosis, no / minimal atypia
Differential diagnosis
