CNS & pituitary tumors

Germ cell tumors

Yolk sac tumor

Last author update: 1 January 2006
Last staff update: 27 August 2020

Copyright: 2002-2023,, Inc.

PubMed Search: Yolk sac tumor CNS

Nat Pernick, M.D.
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Cite this page: Pernick N. Yolk sac tumor. website. Accessed March 30th, 2023.
Definition / general
  • Rare intracranial tumor, usually in pineal or suprasellar regions
  • Also called endodermal sinus tumor
  • Prognosis poorer than germinoma (median survival 2 years or less)
Case reports
Gross description
  • Usually large
Microscopic (histologic) description
  • Tubulopapillary structures with vacuolated cuboidal cells, cystic spaces with eosinophilic hyaline bodies and Schiller-Duval bodies
Positive stains
Additional references
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