Coagulation
Acquired thrombophilia / hypercoagulopathies
Acquired thrombophilia - general
Author: Jeremy C. Parsons, M.D.
Last author update: 1 April 2013
Last staff update: 23 September 2020
Copyright: 2003-2024, PathologyOutlines.com, Inc.
PubMed Search: Acquired thrombophilia [title]
Cite this page: Parsons JC. Acquired thrombophilia - general. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/coagulationacquiredhypercoaggeneral.html. Accessed April 18th, 2024.
Definition / general
- Thrombophilia: any disorder associated with increased risk of venous thromboembolic disease; more appropriately called "hypercoagulable state" if not genetic, although terms often used interchangeably
- Common risk factors are: antiphospholipid antibodies, chronic DIC, essential thrombocythemia, heparin induced thrombocytopenia, hyperhomocysteinemia, immobility, increasing age, malignancy, nephrotic syndrome, obesity, oral contraceptives, paroxysmal nocturnal hemoglobinuria, polycythemia vera, postoperative state, pregnancy, prior thromboembolism, systemic lupus erythematosus, trauma
- Presence of more than one risk factor further increases risk (Arch Pathol Lab Med 2002;126:295)
Case reports
- 33 year old man with fatal pulmonary emboli associated with hypereosinophilia (J Clin Path 2004;57:541)
- 52 year old woman with portal vein thrombosis associated with myeloproliferative disorder (Arch Pathol Lab Med 2003;127:e385)
Clinical images
Images hosted on other servers:
Thrombi in major trunks of pulmonary artery
Additional references
