Coagulation laboratory tests

Factor IX assay

Topic Completed: 1 November 2012

Minor changes: 16 September 2020

Copyright: 2002-2022,, Inc.

PubMed Search: Factor IX assay [title]

Jeremy C. Parsons, M.D.
Page views in 2021: 35
Cite this page: Parsons JC. Factor IX assay. website. Accessed January 17th, 2022.
Definition / general
  • To detect congenital or acquired factor IX deficiency
  • Congenital factor IX deficiency (hemophilia B) is inherited as a sex - linked recessive in 1 per 30,000 males
  • Acquired factor IX deficiency is seen in liver disease, vitamin K deficiency, Coumadin therapy
  • A linear, dose - dependent, false decrease is caused by bivalirudin, lepirudin, argatroban, and fondaparinux (Arch Pathol Lab Med 2004;128:1142)
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