Coagulation

Coagulation laboratory tests

Factor IX assay



Topic Completed: 1 November 2012

Minor changes: 16 September 2020

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PubMed Search: Factor IX assay [title]

Jeremy C. Parsons, M.D.
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Cite this page: Parsons JC. Factor IX assay. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/coagulationfactorIX.html. Accessed October 18th, 2021.
Definition / general
  • To detect congenital or acquired factor IX deficiency
  • Congenital factor IX deficiency (hemophilia B) is inherited as a sex - linked recessive in 1 per 30,000 males
  • Acquired factor IX deficiency is seen in liver disease, vitamin K deficiency, Coumadin therapy
  • A linear, dose - dependent, false decrease is caused by bivalirudin, lepirudin, argatroban, and fondaparinux (Arch Pathol Lab Med 2004;128:1142)
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