Thrombolytic therapy

Topic Completed: 1 June 2012

Minor changes: 23 September 2020

Copyright: 2002-2021,, Inc.

PubMed Search: Thrombolytic therapy [title]

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Cite this page: Parsons JC. Thrombolytic therapy. website. Accessed January 22nd, 2021.
Definition / general
  • Used to treat myocardial infarction, pulmonary embolism, arterial or venous thrombosis, thrombotic stroke
  • Thrombolytic agents include recombinant t-PA, urokinase, streptokinase (only tPA is widely available in the USA)
Diagrams / tables

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t-PA action

  • Presence of fibrin degradation products and D-dimers, decreased fibrinogen and plasminogen, prolonged thrombin time, PT and PTT
Additional references
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