Diverticular disease


Topic Completed: 1 September 2014

Minor changes: 30 September 2020

Copyright: 2003-2021,, Inc.

PubMed Search: colon diverticulitis[title]

Hanni Gulwani, M.B.B.S.
Page views in 2020: 5,474
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Cite this page: Gulwani H. Diverticulitis. website. Accessed October 28th, 2021.
Definition / general
Clinical features
  • Clinically may resemble appendicitis
Case reports
  • Liquid diet (bowel rest) and oral antibiotics; surgical resection if perforation, fistula, obstruction, persistent pain, hemorrhage, repeated attacks or immunocompromise (J Clin Gastroenterol 2006;40:S145)
Gross images

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Acute diverticulitis

Acute and chronic disease

Diverticulitis with perforation

Microscopic (histologic) description
  • Acute or chronic inflammatory infiltrate near base of diverticula; occasionally granulomatous inflammation
Microscopic (histologic) images

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Perforated diverticulum

Multiple diverticula

Diverticula in sigmoid colon

Fecal granuloma associated with perforation

Differential diagnosis
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