Colon nontumor
Nonneoplastic, non-congenital lesions

Topic Completed: 1 September 2013

Revised: 9 January 2019 last major update September 2013

Copyright: (c) 2003-2018,, Inc.

PubMed Search: gout colon

Raul S. Gonzalez, M.D.
Page views in 2019: 530
Page views in 2020 to date: 219
Cite this page: Gonzalez R. Gout. website. Accessed May 30th, 2020.
Definition / general
  • Clinical syndrome due to deposition of urate crystals
  • See topic in joints chapter
  • Tophus: deposit of urate crystals, typically in joints or soft tissue
  • Extremely rare in colon - only one reported case
  • Disturbance in purine metabolism leads to increased levels of urate, causing deposits that incite an inflammatory reaction
Clinical features
  • Abdominal pain in colonic gout
Case reports
  • Pharmacologic
  • Resection of mass lesions if symptomatic
Gross description
  • Subserosal colonic cyst filled with white-yellow chalky material
Microscopic (histologic) description
  • Subserosal colonic cyst containing needle-shaped polarizable urate crystals (identified with alcohol, not formalin fixation) with surrounding reactive changes
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