Colon tumor
Glassy cell carcinoma

Topic Completed: 1 March 2015

Minor changes: 25 June 2019

Copyright: 2002-2019,, Inc.

PubMed Search: Glassy cell carcinoma [title]

Raul S. Gonzalez, M.D.
Page views in 2019: 324
Page views in 2020 to date: 183
Cite this page: Gonzalez R. Glassy cell carcinoma of colon. website. Accessed May 24th, 2020.
Definition / general
Microscopic (histologic) description
  • Sheets of malignant cells with ground glass, finely granular cytoplasm
  • Enlarged nuclei with prominent nucleoli
  • Multinucleated cells common
  • Abundant mitotic figures
Microscopic (histologic) images

Images hosted on other servers:

From cervix

Positive stains
Electron microscopy description
  • Prominent rough endoplasmic reticulum
Differential diagnosis
  • Poorly differentiated colorectal carcinoma: glassy cytoplasm absent
  • Focal hCG positivity / production by other carcinomas: more common; other morphologic features absent
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