Other tumors

Mantle cell lymphoma

Last author update: 1 February 2012
Last staff update: 3 May 2022

Copyright: 2003-2022,, Inc.

PubMed Search: Mantle cell lymphoma colon

Page views in 2021: 4,184
Page views in 2022 to date: 2,191
Cite this page: Singh C. Mantle cell lymphoma. website. Accessed July 5th, 2022.
Definition / general
Case reports
Gross description
  • Nodular, sessile or polypoid lesions, widely spaced and confluent studded or cobblestone appearance
  • Each polyp 2 mm to 2 cm
  • May be dominant tumor mass in ileocecum
  • Endoscopically normal mucosa may have small tumor infiltrates also
Gross images

Images hosted on other servers:

Lymphomatoid polyposis

Microscopic (histologic) description
  • Mantle cells (small lymphocytes with pale cytoplasm and cleaved nuclei), often invasion of submucosa, proliferation around germinal centers and sparing of mucosa
  • Late epithelial invasion and ulceration
  • Note: may also be minute lymphoid infiltrates in known mantle cell patients
Microscopic (histologic) images

Images hosted on other servers:

80 year old woman

Positive stains
Negative stains
Differential diagnosis
Back to top
Image 01 Image 02