Ear
Inflammatory / infectious / autoimmune / systemic disorders
Myospherulosis
Author: Nat Pernick, M.D.
Last author update: 1 October 2013
Last staff update: 14 December 2020
Copyright: 2002-2023, PathologyOutlines.com, Inc.
PubMed Search: Myospherulosis ear
Table of Contents
Definition / general | Case reports | Treatment | Gross description | Microscopic (histologic) description | Negative stainsCite this page: Pernick N. Myospherulosis. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/earmyospherulosis.html. Accessed June 3rd, 2023.
Definition / general
- Iatrogenic due to petrolatum based ointments
- Usually nasal cavity and paranasal sinuses; occasionally affects middle ear
- History of recent surgery with packing of area (Am J Clin Pathol 1977;67:118)
- Associated with postoperative adhesions after sinus surgery (Laryngoscope 2003;113:1123)
Case reports
- 48 year old woman with myospherulosis of the middle ear (Laryngorhinootologie 2004;83:445)
- Patient with myospherulosis in the operated temporal bone (Eur Arch Otorhinolaryngol 1992;249:231)
Treatment
- Symptomatic
Gross description
- Ointment like material within granulation tissue
Microscopic (histologic) description
- Pseudocysts within fibrous tissue with lymphocytes, histiocytes, giant cells and plasma cells
- Pseudocysts contain "parent bodies" containing numerous spherules
Negative stains
- GMS for fungi
