Esophagus

Esophagitis

CMV



Last author update: 1 September 2012
Last staff update: 21 December 2020

Copyright: 2003-2022, PathologyOutlines.com, Inc.

PubMed Search: CMV cytomegalovirus esophagus[TIAB]


Elliot Weisenberg, M.D.
Page views in 2021: 3,497
Page views in 2022 to date: 2,480
Cite this page: Weisenberg E. CMV. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/esophagusCMVesophagitis.html. Accessed August 17th, 2022.
Definition / general
Diagnosis
  • Histology is necessary to confirm diagnosis; repeat biopsy may be necessary
Case reports
Treatment
Gross description
Microscopic (histologic) description
  • Virus present in enlarged endothelium and stromal cells at ulcer base
  • Basophilic cytoplasm often has coarse intracytoplasmic granules
  • Prominent intranuclear basophilic inclusions surrounded by clear halo
  • Macrophage aggregates in perivascular distribution are somewhat specific for CMV or HSV (Hum Pathol 1997;28:375); features are less obvious in patients receiving antiviral therapy
  • Inclusions are generally numerous but may be atypical in HIV patients (Hum Pathol 1992;23:1019)
Microscopic (histologic) images

Images hosted on other servers:

CMV and leishmaniasis

Positive stains
  • CMV immunostain or in situ hybridization
Back to top
Image 01 Image 02