Other nonneoplastic


Topic Completed: 1 January 2013

Minor changes: 17 December 2020

Copyright: 2003-2021,, Inc.

PubMed Search: Melanocytosis esophagus

Elliot Weisenberg, M.D.
Page views in 2020: 676
Page views in 2021 to date: 714
Cite this page: Weisenberg E. Melanocytosis. website. Accessed October 22nd, 2021.
Definition / general
Gross description
  • No abnormalities
Microscopic (histologic) description
  • Melanocytic proliferation in basal layer of esophageal squamous epithelium with increased quantity of melanin; overlying epithelium may demonstrate hyperplasia, acanthosis or hyperkeratosis; variable inflammation, melanophages, fibrosis and telangiectasia; no atypia
Positive stains
Negative stains
Electron microscopy description
Differential diagnosis
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