Cicatrizing conjunctivitis

Topic Completed: 1 September 2013

Minor changes: 22 December 2020

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PubMed Search: Cicatrizing conjunctivitis

Deepali Jain, M.D.
Page views in 2020: 408
Page views in 2021 to date: 455
Cite this page: Jain D. Cicatrizing conjunctivitis. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/eyecicatrizingconj.html. Accessed December 6th, 2021.
Definition / general
  • Cicatrizing: causing a scar and possibly affecting vision
  • Conjunctival fibrosis due to chronic inflammation, leading to alterations of conjunctival architecture
Clinical features
  • Dry eyes
  • Loss of transparency and vision
  • Positive direct immunofluorescence with IgA, IgM, IgG, complement C3, complement C4, and fibrinogen in autoimmune diseases
  • Medical management varies according to specific causes
Microscopic (histologic) description
  • Fibrosis and inflammation consisting of neutrophils, lymphocytes, plasma cells
  • Keratinization of superficial layer, hyperplasia of basal layers
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